Ian A Wilson Selected Research

Broadly Neutralizing Antibodies

2/2022	Targeted isolation of panels of diverse human protective broadly neutralizing antibodies against SARS-like viruses.
1/2022	A human antibody reveals a conserved site on beta-coronavirus spike proteins and confers protection against SARS-CoV-2 infection.
1/2022	A human antibody reveals a conserved site on beta-coronavirus spike proteins and confers protection against SARS-CoV-2 infection.
12/2021	A combination of cross-neutralizing antibodies synergizes to prevent SARS-CoV-2 and SARS-CoV pseudovirus infection.
2/2021	A combination of cross-neutralizing antibodies synergizes to prevent SARS-CoV-2 and SARS-CoV pseudovirus infection.
1/2021	Functional convergence of a germline-encoded neutralizing antibody response in rhesus macaques immunized with HCV envelope glycoproteins.
1/2020	Different genetic barriers for resistance to HA stem antibodies in influenza H3 and H1 viruses.
1/2020	An influenza A hemagglutinin small-molecule fusion inhibitor identified by a new high-throughput fluorescence polarization screen.
1/2020	Convergent Evolution in Breadth of Two VH6-1-Encoded Influenza Antibody Clonotypes from a Single Donor.
10/2018	Recurring and Adaptable Binding Motifs in Broadly Neutralizing Antibodies to Influenza Virus Are Encoded on the D3-9 Segment of the Ig Gene.

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Ian A Wilson Research Topics

Disease

71	Human Influenza (Influenza) 01/2022 - 09/2005
58	Infections 04/2022 - 07/2005
31	COVID-19 04/2022 - 01/2020
11	Neoplasms (Cancer) 01/2021 - 05/2002
8	Amyloidosis 01/2022 - 02/2010
7	Influenza in Birds (Avian Flu) 01/2018 - 02/2006
5	Malaria 01/2022 - 11/2017
5	Virus Diseases (Viral Diseases) 01/2021 - 01/2018
4	Cardiomyopathies (Cardiomyopathy) 01/2017 - 08/2011
3	Alzheimer Disease (Alzheimer's Disease) 12/2018 - 01/2017
2	Inflammation (Inflammations) 01/2021 - 09/2010
2	Weight Loss (Weight Reduction) 11/2020 - 08/2020
2	Leukemia 12/2017 - 07/2013
2	Familial Amyloid Neuropathies (Familial Amyloid Polyneuropathy) 01/2017 - 06/2012
2	Cocaine-Related Disorders (Cocaine Addiction) 02/2015 - 10/2002
2	Acquired Immunodeficiency Syndrome (AIDS) 05/2014 - 07/2011
2	Disease Progression 06/2012 - 11/2008
2	Communicable Diseases (Infectious Diseases) 04/2012 - 11/2010
2	Autoimmune Diseases (Autoimmune Disease) 06/2007 - 12/2005
1	Measles 12/2021
1	Lymphopenia (Lymphocytopenia) 10/2021
1	Asthma (Bronchial Asthma) 01/2021
1	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 01/2021
1	Bites and Stings (Sting) 01/2021
1	Glomerulonephritis 01/2021
1	Chronic Obstructive Pulmonary Disease (COPD) 01/2021
1	Uterine Cervical Neoplasms (Cancer of the Cervix) 01/2020
1	Hyperalgesia 10/2016
1	Pain (Aches) 10/2016

Drug/Important Bio-Agent (IBA)

51	Hemagglutinins (Hemagglutinin)IBA 01/2022 - 09/2005
37	VaccinesIBA 01/2022 - 11/2006
33	Proteins (Proteins, Gene)FDA Link 04/2022 - 10/2007
33	AntibodiesIBA 01/2022 - 03/2006
26	Broadly Neutralizing AntibodiesIBA 02/2022 - 12/2011
20	Monoclonal AntibodiesIBA 04/2022 - 08/2011
16	Neutralizing AntibodiesIBA 03/2022 - 09/2008
16	EpitopesIBA 02/2022 - 04/2009
9	Polysaccharides (Glycans)IBA 01/2022 - 02/2006
9	Glycoproteins (Glycoprotein)IBA 01/2021 - 09/2008
8	Neuraminidase (Sialidase)IBA 12/2021 - 11/2008
8	Influenza Vaccines (Influenza Vaccine)FDA Link 01/2020 - 11/2010
7	AntigensIBA 01/2022 - 05/2002
5	Peptides (Polypeptides)IBA 04/2022 - 05/2002
5	Surface Antigens (Surface Antigen)IBA 01/2020 - 04/2009
5	Antiviral Agents (Antivirals)IBA 01/2020 - 04/2012
5	Prealbumin (Transthyretin)IBA 01/2017 - 02/2010
5	Membrane Glycoproteins (Membrane Glycoprotein)IBA 03/2015 - 07/2011
4	Immunoglobulin Light Chains (Immunoglobulin Light Chain)IBA 01/2022 - 06/2013
3	Pharmaceutical PreparationsIBA 04/2022 - 06/2013
3	EnzymesIBA 01/2019 - 12/2002
3	Amyloid (Amyloid Fibrils)IBA 06/2013 - 08/2011
3	DNA (Deoxyribonucleic Acid)IBA 09/2012 - 06/2007
3	LigandsIBA 08/2011 - 03/2006
2	Angiotensin-Converting Enzyme 2IBA 04/2022 - 01/2021
2	SARS-CoV-2 spike proteinIBA 01/2022 - 01/2022
2	Sialic AcidsIBA 01/2022 - 05/2012
2	Transcription Factors (Transcription Factor)IBA 12/2021 - 03/2016
2	Bispecific AntibodiesIBA 10/2021 - 04/2021
2	Biological ProductsIBA 01/2021 - 01/2018
2	CV07-209IBA 11/2020 - 08/2020
2	Immunoglobulin M (IgM)IBA 01/2020 - 01/2018
2	tau Proteins (tau Protein)IBA 12/2018 - 01/2018
2	Immunoglobulin G (IgG)IBA 01/2018 - 03/2006
2	AIDS VaccinesIBA 11/2017 - 01/2015
2	umifenovirIBA 10/2017 - 01/2017
2	LipidsIBA 01/2017 - 01/2016
2	N-Acetylneuraminic Acid (Sialic Acid)IBA 01/2017 - 01/2013
2	tafamidisIBA 01/2017 - 06/2012
2	Carrier Proteins (Binding Protein)IBA 02/2016 - 10/2013
2	Viral HemagglutininsIBA 03/2015 - 01/2011
2	Mannose (D-Mannose)IBA 01/2015 - 05/2014
2	DiglyceridesIBA 10/2009 - 09/2006
2	GlycolipidsIBA 09/2006 - 12/2005
1	aminoadamantane nitrateIBA 04/2022
1	Protein SIBA 04/2022
1	PhosphoproteinsIBA 12/2021
1	Single-Domain AntibodiesIBA 12/2021
1	COVA1-18IBA 10/2021
1	Cytokine Receptors (Cytokine Receptor)IBA 01/2021
1	Immunoglobulin A (IgA)IBA 01/2021
1	cibisatamabIBA 01/2020
1	Immunoglobulins (Immunoglobulin)IBA 01/2020
1	Viral ProteinsIBA 01/2020
1	Biomarkers (Surrogate Marker)IBA 01/2020
1	Membrane Proteins (Integral Membrane Proteins)IBA 01/2019
1	EndonucleasesIBA 11/2018
1	MetalsIBA 11/2018
1	DNA-Directed RNA Polymerases (RNA Polymerase)IBA 11/2018
1	EsterasesIBA 10/2018
1	Indicators and Reagents (Reagents)IBA 12/2017
1	rimabotulinumtoxinB FDA Link 10/2017
1	N-acetyllactosamineIBA 01/2017
1	CytokinesIBA 10/2016
1	HMGB1 Protein (HMG1)IBA 10/2016
1	RNA Splicing FactorsIBA 04/2016
1	RNA-Binding Proteins (RNA-Binding Protein)IBA 04/2016

Therapy/Procedure

21	Therapeutics 04/2022 - 09/2003
5	Immunotherapy 01/2020 - 09/2003
2	Critical Care (Surgical Intensive Care) 04/2021 - 07/2020
1	Oral Administration 01/2019